Quote:
Originally Posted by docicu3
Doug
In the human world we "overshoot" coumadin or warfarin doses all the time which is easily treated by Vit K or time, often the problem isn't the drug but whatever else is eaten with the meal which can either shorten or lengthen the half life of the drug since they all work by interfering with Vit K metabolism or the liver dependent coagulation factors.Vitamin K is used in the body to form bones but also plays an important role in blood clotting. Coumadin works by interfering with the liver synthesis of vitamin K-dependent clotting factors. Vit K decreases the amount of blood clots formed in the body the opposite of what your drugs in the article do.
In humans we use these meds to stop clotting for a bunch of reasons such as stroke prevention or avoiding clot associated with abnormal heart rythmns but yes these are the same class and effect of drugs.
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what else would be affected? would it affect overall metabolism? would there be anything beneficial from using blood thinners for someone/thing in high activity?