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Originally Posted by RolloTomasi
You're using hindsight with respect to Devil May Care. She wasn't diagnosed with lymposarcoma until just prior to being euthanized.
What was so "very different" about the abnormalities displayed between the two horses?
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"Off-feed, losing weight, and performing poorly" can presage hundreds of medical problems, from pneumonia to a tooth abcess.
DMC had a different liver enzyme profile, and didn't respond well to treatment from day one. That's often pathognomonic for lymphosarcoma, which yes, can be difficult to diagnose even with biopsy/imaging until very late in the disease course, especially when the animal is put on glucocorticoids to help treat the presenting clinical symptoms (as that dampens down many markers of the clinical presentation of lymphosarcoma, and extends life)
UM responded well from day one, with a different blood profile, and a small relapse with a subacute cholangiohepatis isn't an uncommon sequela to a GI tract infection.
The different hepatic conditions present clearly differently upon a good diagnostic workup: liver/lymph biopsy, diagnostic imaging (ultrasound), bloodwork, response to different treatments, etc.
What was relayed publicly about both horses was entirely consistent with the subsequent individual conditions announced, and inconsistent with much of the casual speculation.
That's my opinion. Others may feel free to continue to mock it.
Good luck to Uncle Mo, I hope he gets back to racing. Training for breeding season doesn't start until December.